This analysis concerns the amyloid form that is listed in PDB as 5O3O, 5O3L, and 5O3T (pronase-treated paired helical filament in Alzheimer’s disease brain neurofibrillary tangle protein, paired helical filament-tau, phf-tau, Homo sapiens). This evidence concerns the gene MAPT and early-onset autosomal dominant Alzheimer disease.