AKT1 and systemic lupus erythematosus: Other results from our group show that IL-10 gene expression in SLE patients correlates with CD38 gene expression; moreover, CD38 expression correlates with AKT serine/threonine kinase 1 (AKT1) expression [2], and in human T and B cells CD38 receptor stimulation leads to Protein Kinase B (PKB)/AKT and Extracellular signal-Regulated protein Kinase (ERK) activation [3].