ABCB1 and congenital heart disease: A Han Chinese study found that maternal occupational exposure to phthalates and alkylphenolic compounds were associated with a higher incidence of total congenital heart defects, with ORs 1.6 (95% CI: 1.0, 2.6) and 1.8 (95% CI: 1.1, 3.0) respectively, but it was found that infants carrying the ABCB1 gene C3435T polymorphism were at greater risk, particularly for septal defects [71].