INS and chronic kidney disease: These baseline results are presented to address two objectives: 1) to characterize measures of vascular stiffness and central pressure in persons meeting the SPRINT inclusion criteria[13], and 2) to test the hypotheses that vascular stiffness and central pressure are associated with markers of glucose homeostasis (fasting glucose, insulin, hemoglobin A1C) renin, aldosterone, and markers associated with CKD (serum calcium, phosphorous, parathyroid hormone, uric acid, and urine albumin-to-creatinine ratio (UACR)).