Recent studies showed that exosomal lncRNAs play an important role in signal exchange between tumor cells, the local microenvironment, or distal target organs.15 In the present study, analysis of a lncRNA lung cancer tissue microarrays revealed differences in exosomal lncRNA expression based on cancer status and identified lnc‐MMP2‐2 as exhibiting high degrees of differential expression during this process. Here, MMP23B is linked to lung cancer.