SHBG and type 2 diabetes mellitus: In a meta‐analysis of 13 population‐based studies with 1912 incident cases of T2DM, low SHBG was associated with increased risk of T2DM in women, irrespective of menopausal status.37 SHBG levels are typically higher in women, and our data confirm that reduced circulating concentrations are associated with a higher risk of T2DM than that observed in men.