The secretion of osteoblast‐derived GAS6 ligands by this niche can induce tumour cells to increase the ratio of GAS6 receptor Axl expression to Tyro3 expression which leads to a more dormant phenotype.66 DTCs recovered from the bone marrow are regulated by GAS6 through the MER/mTOR pathway, exhibiting a stem cell–like phenotype.67 This evidence concerns the gene GAS6 and neoplasm.