NDUFB8 and idiopathic pulmonary fibrosis: In addition, genes involved in regulating mitochondrial synthesis (PGC‐1α) or components of the mitochondrial electron transport chain (UQCRC2 and NDUFB8) were up‐regulated in IPF‐LFs (Figure 2D), concomitantly with an increase in the activity of mTORC1, a pivotal mediator of mitochondrial homoeostasis (Figure 2E).