These include a thrombophilia (coagulation screen, protein C&S, factor V Leiden, anti-phospholipid, plasminogen activator) [1, 2, 20] and autoimmune/vasculitic screen (ANA, anti-double stranded DNA antibody, ANCA, lupus anticoagulant, anticardiolipin antibody) [2, 20]. Here, F5 is linked to thrombophilia.