To list a few genes (Tables 2 and 3), FTO (rs10521308, p value = 9.47E-05) and CTNNBL1 (rs2206135, p value = 7.75E-05) have both been strongly associated with obesity risk and related traits [24, 25]. This evidence concerns the gene CTNNBL1 and obesity due to melanocortin 4 receptor deficiency.