FSTL5 overexpression also decreased tumor volume and weight of Bel7404 cell xenografts by 44.1% and 51.4%, respectively; tumor volume: control: 397.2 ± 106.1 mm3 vs FSTL5: 222 ± 109.7 mm3; and tumor weight: control: 0.321 ± 0.074 g vs FSTL5: 0.156 ± 0.026 g) (Figure 7F and G). This evidence concerns the gene FSTL5 and neoplasm.