The stromal expression of αSMA and CD34 (see Figs 7 and 8) significantly increases in PCa tissue - as compared to PNT tissue - in each GS group for αSMA (Sign test: p = 0.007 for GS6, p = 0.054 for GS7 and p = 0.005 for GS8) and in GS7 and GS8 only for CD34 (Sign test: p = 0.021 for GS7 and p < 0.001 for GS8) (Fig. 9). This evidence concerns the gene ACTA1 and posterior cortical atrophy.