In the original version of this Article, the sixth sentence of the abstract incorrectly read ‘Most of the genes upregulated and with hypermethylated CGIs in the Alb-R26Met HCC model undergo the same change’, and should have read ‘Most of the genes upregulated and with hypermethylated CGIs in the Alb-R26Met HCC model undergo the same change in a large proportion of HCC patients’. This evidence concerns the gene ALB and hepatocellular carcinoma.