ADAR and neoplasm: To investigate the situation in tumour tissues, we correlated the expression of ADAR transcripts with expression of edited CCNI. This analysis revealed higher correlation for ADAR1 (R = 0.48, CI = 0.47–0.50, Supplementary Fig. 5b) than for ADAR2 (R = 0.28, CI = 0.26–0.30) or ADAR3 (R = 0.07, CI = 0.05–0.10) suggesting ADAR1 as most likely enzyme responsible for catalysing the editing.