Previous genome-wide association study (GWAS) identified the PRKAA1 polymorphism rs13361707 as a risk factor for non-cardiac GC (NCGC) in a Chinese population [8]; however, these results were not successfully duplicated [9], which may be due to the different characteristics of enrolled participants, population stratification, and clinical pathologic characteristics of GC. This evidence concerns the gene PRKAA1 and gastric cancer.