MMP2 and diabetic kidney disease: Moreover, we tried to explore the expression of two isoforms of MMP-2 in diabetic kidney and firstly reported on the enhanced tubular epithelial cell expression of the FL-MMP-2 and NTT-MMP-2 isoforms in the murine streptozotocin model of Type 1 diabetes mellitus and in archival renal biopsies from patients with diabetic nephropathy [9].