But diminished IFN-γ response in children born to infected mother has been predicted to bias the immune response towards development of T regulatory and Th2 responses rather than Th1 responses [7].Moreover a negative correlation between IFN-γ and IL-10 observed among the infected children born to infected mother highlights epigenetic changes within the naïve T cell compartment affecting Th2 and Th1 cell differentiation as described by others in offspring of mothers with chronic helminthic infection [21, 22]. This evidence concerns the gene IFNG and helminthiasis.