MLH1 and mismatch repair cancer syndrome 1: The accumulation (i.e., > 15%) of MMR deficiency reported in CRC diagnosed at age ≥ 60 years due to somatic MLH1 promoter methylation (Bapat et al. 2009) was not observed in our cohort (< 7%; 3/45 cases), the discrepancy which possibly reflects the few elderly in our study.