Specifically, PRKDC (Figure 5a,b) ranked 17th and 23th by MaxMIF with HumanNet and STRINGv10, has been reported as an essential gene required for colorectal cancer cells.32EGF (epidermal growth factor, Figure 5a,b), ranked 133th and 432th by MaxMIF with HumanNet and STRINGv10, plays an important role in nonsmall cell lung cancer (NSCLC).33RAD51 (Figure 5a–c), ranked 140th and 480th by MaxMIF with HumanNet and STRINGv10 is known to interact with the breast cancer driver gene BRCA2. 34. The gene discussed is PRKDC; the disease is breast cancer.