Another study, a meta-analysis, concluded that S100 calcium-binding protein P (S100P) shows high sensitivity (0.87; 95% CI, 0.83–0.90) and specificity (0.88; 95% CI, 0.82–0.93) for pancreatic cancer diagnosis (Hu et al., 2014). This evidence concerns the gene S100P and familial pancreatic carcinoma.