Next, we observed that miR-490-3p overexpression greatly attenuated migration of ovarian cancer cells SKOV3 and CaOV3, whereas exogenous expression of miR-490-3p and TGFβR1 rescued TGFβ1-induced migration change of the cells (Fig. 5e, f). The gene discussed is TGFB1; the disease is ovarian cancer.