TGFB1 and diabetes mellitus: In line with this hypothesis, miR-192 was increased in mouse mesangial cells treated with TGF-β1 and in renal glomeruli from mouse models of diabetes depicting early stages of diabetic nephropathy (streptozotocin-injected type-1 diabetic mice and type-2 diabetic db/db mice) compared to nondiabetic control mice49,55,57.