A previous study has shown that inhibiting the function of MCL-1 in H1299 by exogenous expression of NOXA sensitized cells to ABT-737, suggesting that the MCL-1 expression level determines the resistance to the inhibition of BCL-2/BCL-xL/BCL-w in NSCLC cells32. Here, BCL2L1 is linked to non-small cell lung carcinoma.