Gu et al. (2017) furthered the study about the effects of OC on STAT3 target genes, including myeloid leukemia cell differentiation (Mcl-1), vascular endothelial growth factor (VEGF), B-cell lymphoma-extra large (Bcl-xL), and matrix metalloproteinase-2 and -9 (MMP-2/9) genes [74]. The gene discussed is MMP2; the disease is myeloid leukemia.