SNAI2 and ovarian carcinoma: Consistent with these results, luciferase assays showed that overexpressing YAP1 promoted the luciferase activity of the wt-Slug-Luc promoter, whereas overexpressing YAP1 had no influence on the luciferase activity of the mut-Slug-Luc promoter (Fig. 7o; P < 0.01); These results illustrated that Slug is a target gene of YAP1 and MLK7-AS1/miR-375/YAP1 axis might promote the EMT program by inducing Slug transcription and thus contribute to ovarian cancer.