The height of the CPP group, but not the z-score of the height, was associated with IGF-2(3580). The BMI of the CPP group, but not the z-score of the BMI, was associated with IGF-2(3580), IGF1R, and the combinations of [IGF-2(3580) + IGF2R], and [IGF-2(3580) + IGFBP-3]. This evidence concerns the gene IGF2 and central precocious puberty.