Other mechanisms discussed are inhibition of the PI3K/AKT pathway in lung cancer cells [23,36], inhibition of the proteasome in rhabdomyosarcoma and hepatoma cells [25,37], and adenosine triphosphate (ATP) depletion by inhibition of glycolysis in stem-like cancer cells [24]. The gene discussed is AKT1; the disease is rhabdomyosarcoma.