The inflammatory effect of λ-carrageenan is explained by its interaction with Toll-like receptor 4 which induces the activation of Nuclear Factor κB (NFκB) and interleukin 8 (IL-8) through a pathway of innate immunity mediated by B-cell CLL/lymphoma 10 [40]. The gene discussed is CXCL8; the disease is B-cell chronic lymphocytic leukemia.