NDP and leprosy: LID-1, NDO-LID, and ND-O-BSA(also named PGL-I), as representative M. leprae-specific antigens, have been widely evaluated as leprosy diagnostics in the hyper-endemic regions of Brazil[20–23], Colombia, the Philippines[24], and China[15] and have been demonstrated to be excellent tools for detecting MB leprosy patients in a simple and highly quantitative manner[24], predicting patients susceptible to developing leprosy type 2 reactions (T2R)[23], and distinguishing leprosy from other confounding dermatoses[18].