NEK4 is one of the Nek family members and overexpressed in lung cancer and colorectal cancer.18, 19 Nek protein family includes 11 subtypes and belongs to serine‐threonine kinases.20 The Nek proteins share substantial homology at the amino terminal domain but exhibit variable homology at the carboxyl region. The gene discussed is NEK4; the disease is colorectal cancer.