Up till now, a number of lncRNAs have been characterized as regulators in HCC cells metastasis process.31 In in vitro experiments, we found that CRNDE facilitated HCC cells metastasis and promoted the EMT progression by decreasing E‐cadherin/Mucin‐1 and increasing Vimentin/Fibronectin. This evidence concerns the gene FN1 and hepatocellular carcinoma.