As shown in Figure 1A, ATF3 serum levels in the NW+CRC and OW/OB+CRC groups were 37.2 and 46.9% higher, respectively, than those in healthy controls (0.59 ± 0.04 vs. 0.43 ± 0.02 ng/mL, P < 0.05) (0.64 ± 0.23 vs. 0.43 ± 0.02 ng/mL, P < 0.01). Here, ATF3 is linked to colorectal carcinoma.