Previous studies on human breast cancer (Wolford et al., 2013), lung cancer (Li et al., 2017), skin cancer (Hao et al., 2013), and CRC (Wu et al., 2014; Yan et al., 2017) have demonstrated increased ATF3 expression in cancer tissues/cells compared with that in normal tissues/cells. The gene discussed is ATF3; the disease is skin neoplasm.