ATF3 and malignant colon neoplasm: Our findings are supported by Wu et al.’s (2014) report, according to which the overexpression of ATF3 promoted the motility and invasiveness of human HT29 and CaCO2 colon cancer cell lines, whereas the knockdown of ATF3 expression using antisense ATF3 oligonucleotides inhibits adhesion and invasion in HT29 colon cancer cells (Ishiguro et al., 2000).