The most enriched (rich factor > 0.02) intestinal pathways were “cell adhesion molecules” (up-regulated in the early stages), “ECM-receptor interaction” (down-regulated in the early stages), “Herpes simplex infection” (up-regulated in the middle stages), “intestinal immune network for IgA production” (up-regulated in the middle stages), “starch and sucrose metabolism” (down-regulated in the middle stages), “galactose metabolism” (down-regulated in the middle stages), and “p53 signaling pathway” (up-regulated in the late stages). Here, TP53 is linked to herpes simplex infectious disease.