It has been reported that MS is associated with oxidative stress and the presence of this state, may favor the oxidation of NO to ONOO−, leading to an increase of metalloproteinases, TGFβ and the degradation of the elastic fibers which in turn, favor the development of aortic aneurisms and rupture via a negative feedback mechanism (Yang W.I. et al., 2010). This evidence concerns the gene TGFB1 and myeloid sarcoma.