DKK3 and urinary bladder carcinoma: DKK‐3 knock‐down by siRNA in T24 human bladder cancer cells inhibited cell growth and induced macropinocytosis and autophagy.16 It also has been recently demonstrated that DKK‐3 is expressed in a subset of OSCC‐derived cell lines including HSC‐4.33 Moreover, in HSC‐4 cells, DKK‐3 knock‐down inhibited migration and invasion.