Meridianin C has previously been reported to inhibit Pim‐1, CDK‐1, CDK‐5, PKA, PKG, GSK‐3β and CK‐1 activity with IC50 values of 1.4, 3, 6, 0.7, 0.4, 2 and 30 μM, respectively.23, 40 There are no reports showing a relationship between cell survival or macropinocytosis induction and those kinases in cancer cells including YD‐10B cells. The gene discussed is CDK5; the disease is cancer.