In the plasma of RCC patients, CXCR2 ligands CXCL1, CXCL3, CXCL5 and CXCL8 are elevated chemokines.42 Furthermore, CXCL7 is a prognostic factor for the overall survival of RCC. The gene discussed is CXCL8; the disease is renal cell adenocarcinoma.