In the plasma of RCC patients, CXCR2 ligands CXCL1, CXCL3, CXCL5 and CXCL8 are elevated chemokines.42 Furthermore, CXCL7 is a prognostic factor for the overall survival of RCC. This evidence concerns the gene CXCL3 and renal cell adenocarcinoma.