A recent initiative to inform SLE management in African patients (the African Lupus Genetics Network) identified underdiagnosis/delayed diagnosis as challenges to care delivery.4 A Zimbabwean study reported that inclusion of the ANA reactivity (dsDNA and Sm) increased the sensitivity of the SLE diagnostic criteria.28 Thus, the inclusion of PCNA may further inform these diagnostic criteria and improve sensitivity. Here, PCNA is linked to systemic lupus erythematosus.