This subgroup was nine times more likely to present with cutaneous symptoms including pruritic, annular or papulosquamous dermatoses that healed without scarring as seen in some forms of cutaneous lupus erythematosus (CLE).42 The coexpression of anti-PCNA and AMA-M2 reactivity may be indicative of a subgroup of patients with the cutaneous variant of lupus and warrants further investigation. This evidence concerns the gene PCNA and systemic lupus erythematosus.