Typically, the host immune response to helminth infection is characterized by the T helper 2 (Th2) response, which involves the production of cytokines interleukin 3 (IL3), IL4, IL5, IL9, and IL13, eosinophilia, goblet, and mast cell hyperplasia, as well as alternatively activated macrophages (2). The gene discussed is IL3; the disease is helminthiasis.