CD40LG and rhinitis: There are no previous, isotype-specific, large-scale data from the bronchial mucosa, but in nasal biopsies from patients with rhinitis Wu et al. (5) found an IgM mutation frequency of ca. 4.5% (comparable to our ca. 4.5% in AA and ca. 5.5% in NANA), and a combined IgA and IgG mutation frequency of about 9%, which is somewhat higher than the 6-7% found in our present data.