LMNB1 and laminopathy: Laminopathies is the dedicated term to call a group of rare genetic disorders caused by mutations in genes encoding proteins of the nuclear lamina: LMNA, coding for lamins A and C, and LMNB1 and LMNB2, coding for lamins B. Laminopathies caused by LMNA mutations are initially defined on clinical criteria’s and is mostly characterized by an autosomal dominant inheritance (Bertrand et al., 2011).