Moreover, finding from the current study has further cemented the efficacy of resveratrol (31) in neurodegenerative diseases, (Li et al., 2012) which suggest that resveratrol (31) was able to inhibit the expression of COX-2 and mPGES-1 in LSP induced microglial cell in a concentration dependent manner. Here, PTGS2 is linked to neurodegenerative disease.