In areas of the appendiceal wall, the nests of signet ring cells coalesced into pools of mucin containing “floating” cells, indicating frank mucinous carcinoma, so-called adenocarcinoma ex-goblet cell carcinoid (Fig. 5), Tang group B. Immunohistochemistry for synaptophysin highlighted scattered occasional peripheral endocrine cells, as is characteristic of goblet cell carcinoid (Fig. 6). Here, SYP is linked to goblet cell carcinoma.