IL18 and tuberculosis: Interestingly, higher scores of factor 1 (high carotenoids and low IL-18) were associated with reduced hazards of TB incidence in both univariable (HR 0.56; 95% CI 0.37–0.82) and multivariable analyses (aHR 0.48; 95% CI 0.26–0.87) (Table 4).