About 30% of the general population have serum CRP levels 3.0–9.9 mg/L, and about 10%–15% have levels>10 mg/L.44 Reasons for elevated CRP in the absence of an infection or chronic inflammatory illness could include obesity, smoking, alcohol use, lack of exercise, so knowledge of CRP levels might prompt participants to adopt a healthier lifestyle. This evidence concerns the gene CRP and obesity due to melanocortin 4 receptor deficiency.