COPS8 and hepatocellular carcinoma: Of 12 identified genes in this prognostic model, three (COPS8, SUGCT and DUSP10) played a protective role in HCC patients, and by contrast the other nine (EIF5B, MNAT1, WASF1, EWSR1, POLR3C, RNF24, PCSK5, NRBP1 and CCDC88A) acted as risk factors for HCC.