TNF and rheumatoid arthritis: It was presented that TNF-α, IL-1β, IL-6, and MMP-9 levels were clearly downregulated in HFLS-RA transfected with miR-410-3p mimics (p < 0.05), whereas they were significantly elevated in HFLS-RA transfected with miR-410-3p inhibitor (p < 0.05) (Fig. 2b–e).