MYH14 and ocular melanoma: At saturating ATP and 50 nM to 500 nM OM, the rate of the faster phase (ka) is similar to the detachment rate of myosin in the absence of OM and the rate of the slow phase (kb) is similar to the detachment rate in the presence of 10 μM OM (Supplementary Fig. 4, Supplementary Table 3).