BRAFV600E/PIK3CAH1047R double-mutant Mice, two months after tumor induction, were treated with either a MEK inhibitor (PD-325901) and a class I Pi3’K inhibitor (GDC-0941) for ten days prior to dissection and LAT1 transcription analysis (Fig. 4b). This evidence concerns the gene SLC7A5 and neoplasm.