RAB3GAP1 and Schnyder corneal dystrophy: Lastly, the RAB3 GTPase Activating Protein Catalytic Subunit 1 (Rab3gap1) has been associated with cardiovascular risk (total cholesterol and HDL) by GWAS association in Framingham Heart Studies [69], with Rab3gap1 loci having associations with an increased risk of SCD [70].