Finally, considerable overlap was seen in Literature Net analysis of the MuRF1−/− significant genes after CH (vs. wild type) (Additional file 4: Figure S2) and the significant genes found in wild-type rat right hearts after CH (Additional file 6: Figure S4), with almost complete overlap (PPARBP, RGS proteins, and ROS1). This evidence concerns the gene ROS1 and cyclic hematopoiesis.