MYH3 encodes embryonic myosin and its mutations contribute to spondylocarpotarsal synostosis (SCT), which is a skeletal disorder characterized by fused vertebrae (including scoliosis and lordosis) and fused carpal and tarsal joints (Cameron-Christie et al. 2018). The gene discussed is MYH3; the disease is spondylocarpotarsal synostosis syndrome.